Multicellular organisms, including humans, are composed of various organs, tissues, and cell types. Although all cells share the same genome, what causes this diversity? Moreover, why do cells arranged in three-dimensional configurations exhibit unique functions based on their spatial locations?
The solution to this mystery lies in spatiotemporal gene expression. The Oki Lab has developed a technique called PIC to comprehensively elucidate genes expressed locally. In addition, ChIP-Atlas, a data-mining suite for exploring epigenomic landscapes, has been developed to unveil the regulatory mechanisms of gene expression. By integrating these two approaches in our research, we are aiming to elucidate the etiology of diseases and advance applications in drug discovery.
News
- 2024-03-02Oki Lab has moved to Kumamoto University.
- 2024-02-20English version of the Oki Lab website has been launched.
- 2023-12-01Mizuki, Ryuichi, and Zhaonan gave presentations at the Gakuhen A [Reproductive Lifespan] NGS meeting 2023.
- 2023-11-02Shinya, Mizuki, and Ryuichi were invited to give talks, and Zhaonan presented a poster at the 96th Ann. Meeting of the JBS.
- 2023-10-25Annotation Tracks and Diff Analysis have been added as part of the major update to ChIP-Atlas.
- 2023-09-25The original research article by Zhaonan, Yuka (alumnus), and Shinya has been published in Epigenetics & Chromatin.
- 2023-09-19Ryuichi has been selected for the JST ACT-X Research and Development Area on "Life Phenomena and Materials".
- 2023-09-10Zhaonan gave a talk as an invited speaker at IIBMP2023.
- 2023-08-19Shinya gave a talk as an invited speaker at the 9th Ann. Meeting of Japan Muscle Society.
- 2023-08-01Shinya was inaugurated as the professor (concurrent) at the Life Resources Research Support Center, Kumamoto Univ.
JA